Welcome to New Madrid, founded in 1783, this charming town in Missouri is steeped in history and culture. Known for the 1811-1812 series of earthquakes that changed the course of the Mississippi River, New Madrid is a must-visit destination for history buffs. With a population of approximately 3,778, this town boasts a unique charm and strong sense of community. New Madrid is also proud to be sister cities with Marbella, Spain, adding an international flair to its small-town charm.